Image analysis

 

Image 1 - Analysis: Magnetic resonance imaging (MRI) of the brain, axial view at the pons level, T1-weighted, showing hypoplasia of the vermis (green arrow) and enlarged posterior fossa.

 

Image 2 - Analysis: Magnetic resonance imaging (MRI) of the brain, axial view at the lateral ventricles level, T2-weighted, lateral ventricles level, showing supratentorial ventricle dilatation (green arrows).

 

Image 3 - Analysis: Magnetic resonance imaging (MRI) of the brain, sagittal view, T1 BRAVO-weighted, midline level, showing partial absence of the corpus callosum (blue arrow) and cerebellar vermis hypoplasia (green arrow), with enlarged posterior fossa.

 

Highlights

        - Dandy Walker malformation consists in the cystic dilatation of the IV ventricle, cerebellar vermis hypoplasia, enlarged posterior fossa, hydrocephaly and median and lateral aperture atresia;

       - Etiopathogenesis is not well defined, although it may be associated with genetic alterations, infectious diseases and prenatal exposure;

       - Intrauterine diagnosis may be performed from the 18^th week with US;

       - Supportive and symptomatic treatment must be established to control complications;

       - Worst prognosis is associated with precocious manifestation of the disease.

References

       - Wilson M, Lindsay D, Levi C, Ackerman T, Gordon W. US case of the day. Dandy-Walker variant with agenesis of the corpus callosum. RadioGraphics. 1994;14(3):678-681.

       - Fonseca M, Vieira M, Nascimento S, Esposito S. Malformação de Dandy-Walker. Revista da Faculdade de Ciências Médicas de Sorocaba. 2017;19(1):4-5.

       - Khan R, De Leon C, Romagna E, Ballardin P. Variante de Dandy Walker – relato de caso. Scientia Medica. 2009;19(4):186-191.

       - Cueva-Núñez J, Lozano-Bustillo A, Irias-Álvarez M, Vásquez-Montes R, Varela-González D. Variante de Dandy Walker: reporte de un caso. Revista Chilena de Pediatría. 2016;87(5):406-410.

       - Monteagudo A, Timor-Tritsch I. Prenatal diagnosis of CNS anomalies other than neural tube defects and ventriculomegaly [Internet]. Uptodate.com. 2018 [cited 22 September 2018]. Available from: http://bit.ly/2IauISU.

       - Bosemani T, Orman G, Boltshauser E, Tekes A, Huisman T, Poretti A. Congenital Abnormalities of the Posterior Fossa. RadioGraphics. 2015;35(1):200-220.

Author

Bruno Campos Santos, 6^th year medical student at Universidade Federal de Minas Gerais.

Email: bruno_campos[at]outlook.com

 

Gessica Roberta Olímpia Piedade Carneiro, 6^th year medical student at Universidade Federal de Minas Gerais.

Email: gessica.olimpia4[at]gmail.com

 

Supervisor

Karla Emília de Sá Rodrigues, MD, Ph.D., Associated Professor and Doctor of the Department of Pediatrics at the Medical School of Universidade Federal de Minas Gerais.

Email: kesrodrigues[at]gmail.com

 

Carlos Magno da Silva, MD, Ph.D., Voluntary Professor and Doctor of the Radiology Service at the Hospital das Clínicas da UFMG.

Email: carlosbresil[at]hotmail.com

                                

Reviewers

Mateus Nardelli, Fernando Amorim, José Nelson Mendes Vieira,  MD, Ph.D., Viviane Santuari Parisotto Marino, MD, Ph.D.

 

Translated by

Bruno Campos Santos, 6^th year medical student at Universidade Federal de Minas Gerais.

E-mail: bruno_campos[at]outlook.com